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Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer

Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-angiogenesis tumor therapy. Herein, we developed PL...

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Detalles Bibliográficos
Autores principales: Kim, Ga Hee, Won, Ji Eun, Byeon, Yeongseon, Kim, Min Gi, Wi, Tae In, Lee, Jae Myeong, Park, Yun-Yong, Lee, Jeong-Won, Kang, Tae Heung, Jung, In Duk, Shin, Byung Cheol, Ahn, Hyung Jun, Lee, Young Joo, Sood, Anil K., Han, Hee Dong, Park, Yeong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096458/
https://www.ncbi.nlm.nih.gov/pubmed/29890852
http://dx.doi.org/10.1080/10717544.2018.1480672