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Imaging the dynamics of transcription loops in living chromosomes

When in the lampbrush configuration, chromosomes display thousands of visible DNA loops that are transcribed at exceptionally high rates by RNA polymerase II (pol II). These transcription loops provide unique opportunities to investigate not only the detailed architecture of pol II transcription sit...

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Detalles Bibliográficos
Autor principal: Morgan, Garry T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096578/
https://www.ncbi.nlm.nih.gov/pubmed/29610944
http://dx.doi.org/10.1007/s00412-018-0667-8