Bioengineered human pseudoislets form efficiently from donated tissue, compare favourably with native islets in vitro and restore normoglycaemia in mice

AIMS/HYPOTHESIS: Islet transplantation is a treatment option that can help individuals with type 1 diabetes become insulin independent, but inefficient oxygen and nutrient delivery can hamper islet survival and engraftment due to the size of the islets and loss of the native microvasculature. We hyp...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Gamble, Anissa, Pawlick, Rena, Pepper, Andrew R., Salama, Bassem, Toms, Derek, Razian, Golsa, Ellis, Cara, Bruni, Antonio, Gala-Lopez, Boris, Lu, Jia (Lulu), Vovko, Heather, Chiu, Cecilia, Abdo, Shaaban, Kin, Tatsuya, Korbutt, Greg, Shapiro, A. M. James, Ungrin, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096633/
https://www.ncbi.nlm.nih.gov/pubmed/29971529
http://dx.doi.org/10.1007/s00125-018-4672-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096633/
https://www.ncbi.nlm.nih.gov/pubmed/29971529
http://dx.doi.org/10.1007/s00125-018-4672-5

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