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Sinomenine attenuates cancer-induced bone pain via suppressing microglial JAK2/STAT3 and neuronal CAMKII/CREB cascades in rat models

Cancer-induced bone pain is one of the most severe types of pathological pain, which often occurs in patients with advanced prostate, breast, and lung cancer. It is of great significance to improve the therapies of cancer-induced bone pain due to the opioids’ side effects including addiction, sedati...

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Detalles Bibliográficos
Autores principales: Chen, Shu-Ping, Sun, Jia, Zhou, Ya-Qun, Cao, Fei, Braun, Cody, Luo, Fang, Ye, Da-Wei, Tian, Yu-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096675/
https://www.ncbi.nlm.nih.gov/pubmed/30027795
http://dx.doi.org/10.1177/1744806918793232