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Sinomenine attenuates cancer-induced bone pain via suppressing microglial JAK2/STAT3 and neuronal CAMKII/CREB cascades in rat models
Cancer-induced bone pain is one of the most severe types of pathological pain, which often occurs in patients with advanced prostate, breast, and lung cancer. It is of great significance to improve the therapies of cancer-induced bone pain due to the opioids’ side effects including addiction, sedati...
Autores principales: | Chen, Shu-Ping, Sun, Jia, Zhou, Ya-Qun, Cao, Fei, Braun, Cody, Luo, Fang, Ye, Da-Wei, Tian, Yu-Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096675/ https://www.ncbi.nlm.nih.gov/pubmed/30027795 http://dx.doi.org/10.1177/1744806918793232 |
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