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Liquid chromatographic nanofractionation with parallel mass spectrometric detection for the screening of plasmin inhibitors and (metallo)proteinases in snake venoms

To better understand envenoming and to facilitate the development of new therapies for snakebite victims, rapid, sensitive, and robust methods for assessing the toxicity of individual venom proteins are required. Metalloproteinases comprise a major protein family responsible for many aspects of veno...

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Detalles Bibliográficos
Autores principales: Zietek, Barbara M., Mayar, Morwarid, Slagboom, Julien, Bruyneel, Ben, Vonk, Freek J., Somsen, Govert W., Casewell, Nicholas R., Kool, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096707/
https://www.ncbi.nlm.nih.gov/pubmed/30090989
http://dx.doi.org/10.1007/s00216-018-1253-x