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Approaching cellular resolution and reliable identification in mass spectrometry imaging of tryptic peptides

On-tissue digestion has become the preferred method to identify proteins in mass spectrometry (MS) imaging. In this study, we report advances in data acquisition and protein identification for MS imaging after on-tissue digestion. Tryptic peptides in a coronal mouse brain section were measured at 50...

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Detalles Bibliográficos
Autores principales: Huber, Katharina, Khamehgir-Silz, Pegah, Schramm, Thorsten, Gorshkov, Vladimir, Spengler, Bernhard, Römpp, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096711/
https://www.ncbi.nlm.nih.gov/pubmed/30066193
http://dx.doi.org/10.1007/s00216-018-1199-z