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Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

Neurotropic herpesviruses can establish lifelong infection in humans and contribute to severe diseases including encephalitis and neurodegeneration. However, the mechanisms through which the brain’s immune system recognizes and controls viral infections propagating across synaptically linked neurona...

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Detalles Bibliográficos
Autores principales: Fekete, Rebeka, Cserép, Csaba, Lénárt, Nikolett, Tóth, Krisztina, Orsolits, Barbara, Martinecz, Bernadett, Méhes, Előd, Szabó, Bálint, Németh, Valéria, Gönci, Balázs, Sperlágh, Beáta, Boldogkői, Zsolt, Kittel, Ágnes, Baranyi, Mária, Ferenczi, Szilamér, Kovács, Krisztina, Szalay, Gergely, Rózsa, Balázs, Webb, Connor, Kovacs, Gabor G., Hortobágyi, Tibor, West, Brian L., Környei, Zsuzsanna, Dénes, Ádám
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096730/
https://www.ncbi.nlm.nih.gov/pubmed/30027450
http://dx.doi.org/10.1007/s00401-018-1885-0