Selective RET kinase inhibition for patients with RET-altered cancers

BACKGROUND: Alterations involving the RET kinase are implicated in the pathogenesis of lung, thyroid and other cancers. However, the clinical activity of multikinase inhibitors (MKIs) with anti-RET activity in RET-altered patients appears limited, calling into question the therapeutic potential of t...

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Detalles Bibliográficos
Autores principales: Subbiah, V, Velcheti, V, Tuch, B B, Ebata, K, Busaidy, N L, Cabanillas, M E, Wirth, L J, Stock, S, Smith, S, Lauriault, V, Corsi-Travali, S, Henry, D, Burkard, M, Hamor, R, Bouhana, K, Winski, S, Wallace, R D, Hartley, D, Rhodes, S, Reddy, M, Brandhuber, B J, Andrews, S, Rothenberg, S M, Drilon, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096733/
https://www.ncbi.nlm.nih.gov/pubmed/29912274
http://dx.doi.org/10.1093/annonc/mdy137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096733/
https://www.ncbi.nlm.nih.gov/pubmed/29912274
http://dx.doi.org/10.1093/annonc/mdy137

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