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TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling

Sinoatrial node fibrosis is involved in the pathogenesis of sinus sick syndrome (SSS). Transient receptor potential (TRP) subfamily M member 7 (TRPM7) is implicated in cardiac fibrosis. However, the mechanisms underlying the regulation of sinoatrial node (SAN) fibrosis in SSS by TRPM7 remain unknown...

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Detalles Bibliográficos
Autores principales: Zhong, Hongbin, Wang, Tingjun, Lian, Guili, Xu, Changsheng, Wang, Huajun, Xie, Liangdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096742/
https://www.ncbi.nlm.nih.gov/pubmed/29511803
http://dx.doi.org/10.1007/s00380-018-1146-0