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TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling
Sinoatrial node fibrosis is involved in the pathogenesis of sinus sick syndrome (SSS). Transient receptor potential (TRP) subfamily M member 7 (TRPM7) is implicated in cardiac fibrosis. However, the mechanisms underlying the regulation of sinoatrial node (SAN) fibrosis in SSS by TRPM7 remain unknown...
Autores principales: | Zhong, Hongbin, Wang, Tingjun, Lian, Guili, Xu, Changsheng, Wang, Huajun, Xie, Liangdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096742/ https://www.ncbi.nlm.nih.gov/pubmed/29511803 http://dx.doi.org/10.1007/s00380-018-1146-0 |
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