Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons

Kv7 channels determine the resting membrane potential of neurons and regulate their excitability. Even though dysfunction of Kv7 channels has been linked to several debilitating childhood neuronal disorders, the ontogeny of the constituent genes, which encode Kv7 channels (KNCQ), and expression of t...

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Detalles Bibliográficos
Autores principales: Telezhkin, Vsevolod, Straccia, Marco, Yarova, Polina, Pardo, Monica, Yung, Sun, Vinh, Ngoc-Nga, Hancock, Jane M., Barriga, Gerardo Garcia-Diaz, Brown, David A., Rosser, Anne E., Brown, Jonathan T., Canals, Josep M., Randall, Andrew D., Allen, Nicholas D., Kemp, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096767/
https://www.ncbi.nlm.nih.gov/pubmed/29797067
http://dx.doi.org/10.1007/s00424-018-2155-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096767/
https://www.ncbi.nlm.nih.gov/pubmed/29797067
http://dx.doi.org/10.1007/s00424-018-2155-7

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