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Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri

Aging is associated with profound changes in the epigenome, resulting in alterations of gene expression, epigenetic landscape, and genome architecture. Class I Histone deacetylases (HDACs), consisting of HDAC1, HDAC2, HDAC3, and HDAC8, play a major role in epigenetic regulation of chromatin structur...

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Detalles Bibliográficos
Autores principales: Zupkovitz, Gordin, Lagger, Sabine, Martin, David, Steiner, Marianne, Hagelkruys, Astrid, Seiser, Christian, Schöfer, Christian, Pusch, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771/
https://www.ncbi.nlm.nih.gov/pubmed/29951776
http://dx.doi.org/10.1007/s00418-018-1687-4