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Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri
Aging is associated with profound changes in the epigenome, resulting in alterations of gene expression, epigenetic landscape, and genome architecture. Class I Histone deacetylases (HDACs), consisting of HDAC1, HDAC2, HDAC3, and HDAC8, play a major role in epigenetic regulation of chromatin structur...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771/ https://www.ncbi.nlm.nih.gov/pubmed/29951776 http://dx.doi.org/10.1007/s00418-018-1687-4 |