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Ammonium [(11)C]thiocyanate: revised preparation and reactivity studies of a versatile nucleophile for carbon-11 radiolabelling

Herein we report the preparation of ammonium [(11)C]thiocyanate via the reaction of [(11)C]CS(2) with ammonia. The [(11)C]SCN(–) ion is demonstrated as a potent nucleophile that can be used to readily generate a range of (11)C-labelled thiocyanate molecules in high conversions. Furthermore, novel (1...

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Detalles Bibliográficos
Autores principales: Haywood, Tom, Cesarec, Sara, Kealey, Steven, Plisson, Christophe, Miller, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096773/
https://www.ncbi.nlm.nih.gov/pubmed/30151085
http://dx.doi.org/10.1039/c7md00425g