Transgene-Assisted Genetic Screen Identifies rsd-6 and Novel Genes as Key Components of Antiviral RNA Interference in Caenorhabditis elegans

RNA interference (RNAi) is a widespread antiviral mechanism triggered by virus-produced double-stranded RNAs (dsRNAs). In Caenorhabditis elegans, antiviral RNAi involves a RIG-I-like RNA helicase, termed DRH-1 (dicer related RNA helicase 1), that is not required for classical RNAi triggered by artif...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Tianyun, Meng, Fei, Lu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096818/
https://www.ncbi.nlm.nih.gov/pubmed/29950414
http://dx.doi.org/10.1128/JVI.00416-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096818/
https://www.ncbi.nlm.nih.gov/pubmed/29950414
http://dx.doi.org/10.1128/JVI.00416-18

Ejemplares similares