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Prognostic relevance of mutations and copy number alterations assessed with targeted next generation sequencing in IDH mutant grade II glioma

BACKGROUND: At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery. METHODS: We used a targeted Next-Generation Sequencing panel to...

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Detalles Bibliográficos
Autores principales: Wijnenga, Maarten M. J., French, Pim J., Dubbink, Hendrikus J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Fleischeuer, Ruth, Dirven, Clemens M. F., Vincent, Arnaud J. P. E., van den Bent, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096891/
https://www.ncbi.nlm.nih.gov/pubmed/29663171
http://dx.doi.org/10.1007/s11060-018-2867-8