Characterization of Behavioral, Signaling and Cytokine Alterations in a Rat Neurodevelopmental Model for Schizophrenia, and Their Reversal by the 5-HT(6) Receptor Antagonist SB-399885

Post-weaning social isolation of rats produces neuroanatomical, neurochemical and behavioral alterations resembling some core features of schizophrenia. This study examined the ability of the 5-HT(6) receptor antagonist SB-399885 to reverse isolation-induced cognitive deficits, then investigated alt...

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Detalles Bibliográficos
Autores principales: Shortall, Sinead E., Negm, Ola H., Fowler, Maxine, Fairclough, Lucy C., Tighe, Patrick J., Wigmore, Peter M., King, Madeleine V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096968/
https://www.ncbi.nlm.nih.gov/pubmed/29423817
http://dx.doi.org/10.1007/s12035-018-0940-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096968/
https://www.ncbi.nlm.nih.gov/pubmed/29423817
http://dx.doi.org/10.1007/s12035-018-0940-0

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