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Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy

Efficient nonviral oral gene delivery offers an attractive modality for chronic protein replacement therapy. Herein, the oral delivery of insulin gene is reported by a nonviral vector comprising a copolymer with a high degree of substitution of branched polyethylenimine on chitosan (CS‐g‐bPEI). Prot...

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Detalles Bibliográficos
Autores principales: Lin, Po‐Yen, Chiu, Ya‐Ling, Huang, Jing‐Huei, Chuang, Er‐Yuan, Mi, Fwu‐Long, Lin, Kun‐Ju, Juang, Jyuhn‐Huarng, Sung, Hsing‐Wen, Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096992/
https://www.ncbi.nlm.nih.gov/pubmed/30128227
http://dx.doi.org/10.1002/advs.201701079