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Interleukin-1 receptor antagonist inhibits angiogenesis in gastric cancer

BACKGROUND: Interleukin-1 alpha (IL-1α) plays an important role in tumorigenesis and angiogenesis of gastric cancer. The interleukin-1 receptor antagonist (IL-1RA) inhibits IL-1 selectively and specifically through IL-1R type I (IL-1RI). However, the underlying mechanism by which IL-1RA modulates th...

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Detalles Bibliográficos
Autores principales: Gong, Zhenqiang, Ma, Jiachi, Su, He, Guo, Tiankang, Cai, Hui, Chen, Quan, Zhao, Xiaodan, Qi, Jianbo, Du, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097079/
https://www.ncbi.nlm.nih.gov/pubmed/29344744
http://dx.doi.org/10.1007/s10147-018-1242-2