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A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

To explore the genetic determinants of obesity and Type 2 diabetes (T2D), the German Center for Diabetes Research (DZD) conducted crossbreedings of the obese and diabetes-prone New Zealand Obese mouse strain with four different lean strains (B6, DBA, C3H, 129P2) that vary in their susceptibility to...

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Detalles Bibliográficos
Autores principales: Vogel, Heike, Kamitz, Anne, Hallahan, Nicole, Lebek, Sandra, Schallschmidt, Tanja, Jonas, Wenke, Jähnert, Markus, Gottmann, Pascal, Zellner, Lisa, Kanzleiter, Timo, Damen, Mareike, Altenhofen, Delsi, Burkhardt, Ralph, Renner, Simone, Dahlhoff, Maik, Wolf, Eckhard, Müller, Timo D, Blüher, Matthias, Joost, Hans-Georg, Chadt, Alexandra, Al-Hasani, Hadi, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097155/
https://www.ncbi.nlm.nih.gov/pubmed/29893858
http://dx.doi.org/10.1093/hmg/ddy217