Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers

BACKGROUND: The Tn neoantigen (GalNAcα1-O-Ser/Thr) is an O-glycan expressed in various types of human cancers. Studies in several Tn-expressing cancer cell lines and pancreatic tumors have identified loss of Cosmc expression caused by either mutations or promoter hypermethylation. In this study, we...

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Detalles Bibliográficos
Autores principales: Sun, Xiaodong, Ju, Tongzhong, Cummings, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097208/
https://www.ncbi.nlm.nih.gov/pubmed/30115016
http://dx.doi.org/10.1186/s12885-018-4708-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097208/
https://www.ncbi.nlm.nih.gov/pubmed/30115016
http://dx.doi.org/10.1186/s12885-018-4708-8

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