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Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers
BACKGROUND: The Tn neoantigen (GalNAcα1-O-Ser/Thr) is an O-glycan expressed in various types of human cancers. Studies in several Tn-expressing cancer cell lines and pancreatic tumors have identified loss of Cosmc expression caused by either mutations or promoter hypermethylation. In this study, we...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097208/ https://www.ncbi.nlm.nih.gov/pubmed/30115016 http://dx.doi.org/10.1186/s12885-018-4708-8 |