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Drug repurposing: Ibrutinib exhibits immunosuppressive potential in organ transplantation

Long-term administration of classic immunosuppressants can induce severe adverse effects. The development of novel immunosuppressants confronts great challenges and opportunities. Ibrutinib, an approved drug for B-cell lineages and chronic graft versus host disease (cGVHD), exhibits immunosuppressiv...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Chen, Jicheng, Gao, Hanchao, Zhang, Song, Zhao, Chengjiang, Zhou, Cuibing, Wang, Chengjun, Li, Yang, Cai, Zhiming, Mou, Lisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097265/
https://www.ncbi.nlm.nih.gov/pubmed/30123049
http://dx.doi.org/10.7150/ijms.24460