Cargando…

Drug repurposing: Ibrutinib exhibits immunosuppressive potential in organ transplantation

Long-term administration of classic immunosuppressants can induce severe adverse effects. The development of novel immunosuppressants confronts great challenges and opportunities. Ibrutinib, an approved drug for B-cell lineages and chronic graft versus host disease (cGVHD), exhibits immunosuppressiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qing, Chen, Jicheng, Gao, Hanchao, Zhang, Song, Zhao, Chengjiang, Zhou, Cuibing, Wang, Chengjun, Li, Yang, Cai, Zhiming, Mou, Lisha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097265/ https://www.ncbi.nlm.nih.gov/pubmed/30123049 http://dx.doi.org/10.7150/ijms.24460

Ejemplares similares

Repurposing of Ibrutinib and Quizartinib as potent inhibitors of necroptosis
por: Huang, Fangmin, et al.
Publicado: (2023)

Structure-Based Virtual Screening Reveals Ibrutinib and Zanubrutinib as Potential Repurposed Drugs against COVID-19
por: Kaliamurthi, Satyavani, et al.
Publicado: (2021)

Ibrutinib repurposing: from B-cell malignancies to solid tumors
por: Massó-Vallés, Daniel, et al.
Publicado: (2016)

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning
por: GAO, Hanchao, et al.
Publicado: (2016)

Circulating Organ-Specific MicroRNAs Serve as Biomarkers in Organ-Specific Diseases: Implications for Organ Allo- and Xeno-Transplantation
por: Zhou, Ming, et al.
Publicado: (2016)

Repurposing ibrutinib: therapeutic effects and implications for translational approaches in Alzheimer’s disease
por: Lee, Hyun-ju, et al.
Publicado: (2023)

Repurposing immunosuppressants for antileukemia therapy
por: Sezaki, Maiko, et al.
Publicado: (2022)

Transcriptome Analysis Reveals the Molecular Mechanisms Underlying Adenosine Biosynthesis in Anamorph Strain of Caterpillar Fungus
por: Lin, Shan, et al.
Publicado: (2019)

Repurposing of an immunosuppressive drug holds promise for stem-cell-based neurorepair
Publicado: (2014)

Re-polarization of immunosuppressive macrophages to tumor-cytotoxic macrophages by repurposed metabolic drugs
por: Oyarce, Cesar, et al.
Publicado: (2021)

The Effect of Immunosuppressive Drugs on MDSCs in Transplantation
por: Yang, Fan, et al.
Publicado: (2018)

Identification of novel diagnostic biomarkers for thyroid carcinoma
por: Wang, Xiliang, et al.
Publicado: (2017)

Immunosuppression for COVID-19: repurposing medicines in a pandemic
por: Shivakumar, Senthuran, et al.
Publicado: (2020)

Drug Interactions between Antimicrobial and Immunosuppressive Agents in Solid Organ Transplant Recipients
por: Bhagat, Vikas, et al.
Publicado: (2021)

Gene based message passing for drug repurposing
por: Wang, Yuxing, et al.
Publicado: (2023)

New immunosuppressive drugs in heart transplantation
por: Costanzo, Maria Rosa
Publicado: (2001)

Repurposing antifungal drugs for cancer therapy
por: Weng, Ningna, et al.
Publicado: (2022)

Drug repurposing for aging research using model organisms
por: Ziehm, Matthias, et al.
Publicado: (2017)

Ibrutinib, a Bruton’s tyrosine kinase inhibitor, exhibits antitumoral activity and induces autophagy in glioblastoma
por: Wang, Jin, et al.
Publicado: (2017)

TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression
por: Gao, Hanchao, et al.
Publicado: (2019)

The Potential of the Combination of CRISPR/Cas9 and Pluripotent Stem Cells to Provide Human Organs from Chimaeric Pigs
por: Feng, Wanyou, et al.
Publicado: (2015)

Ibrutinib in Chronic Lymphocytic Leukemia: Clinical Applications, Drug Resistance, and Prospects
por: Zhou, Hong, et al.
Publicado: (2020)

Network bioinformatics analysis provides insight into drug repurposing for COVID-19
por: Li, Xu, et al.
Publicado: (2021)

A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia
por: Mou, Lisha, et al.
Publicado: (2015)

Tolerance in Organ Transplantation: From Conventional Immunosuppression to Extracellular Vesicles
por: Monguió-Tortajada, Marta, et al.
Publicado: (2014)

Eosinophilic Pustular Folliculitis in the Setting of Solid Organ Transplant Immunosuppression
por: Chen, Jeffrey, et al.
Publicado: (2023)

Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
por: Burke, Jacqueline A., et al.
Publicado: (2022)

Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review
por: Boulay, Hugoline, et al.
Publicado: (2021)

Study on a New Method of Link-Based Link Prediction in the Context of Big Data
por: Jicheng, Chen, et al.
Publicado: (2021)

Real clinical impact of drug–drug interactions of immunosuppressants in transplant patients
por: Gago‐Sánchez, Ana Isabel, et al.
Publicado: (2021)

Ibrutinib-induced cardiomyopathy
por: Kyi, Htay Htay, et al.
Publicado: (2019)

Extrahepatic metabolism of ibrutinib
por: Rood, Johannes J. M., et al.
Publicado: (2020)

Ibrutinib is not an effective drug in primografts of TCF3-PBX1
por: van de Ven, Cesca, et al.
Publicado: (2020)

Editorial: Drug Repurposing
por: Pantziarka, Pan, et al.
Publicado: (2019)

Antifungal Drug Repurposing
por: Kim, Jong H., et al.
Publicado: (2020)

Drug repurposing in cardiology
por: van Driel, B. O., et al.
Publicado: (2020)

Machine Learning Applications in Drug Repurposing
por: Yang, Fan, et al.
Publicado: (2022)

Repurposing of antiviral drugs for COVID-19 and impact of repurposed drugs on the nervous system
por: Punekar, Madhura, et al.
Publicado: (2022)

Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity
por: Mackie, Emily R. R., et al.
Publicado: (2023)

Ibrutinib Monotherapy as Bridge-to-Transplant for Relapsed/Refractory Primary Oculo-Cerebral Lymphoma
por: Deak-Mihaly, Dalma, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_miqtvm7vi0lgifkdlri4ijo5ph