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Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element
BACKGROUND: The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development. Little is known of the role of Oct4 in DNA methylation in mic...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097287/ https://www.ncbi.nlm.nih.gov/pubmed/30140294 http://dx.doi.org/10.1186/s11658-018-0104-2 |