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Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element

BACKGROUND: The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embryonic development. Little is known of the role of Oct4 in DNA methylation in mic...

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Detalles Bibliográficos
Autores principales:	Wu, Fengrui, Wu, Qingqing, Li, Dengkun, Zhang, Yuan, Wang, Rong, Liu, Yong, Li, Wenyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097287/ https://www.ncbi.nlm.nih.gov/pubmed/30140294 http://dx.doi.org/10.1186/s11658-018-0104-2

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