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Healthcare resource utilization in the management of hypophosphatasia in three patients displaying a spectrum of manifestations
BACKGROUND: Hypophosphatasia (HPP) is a rare, heterogeneous disease caused by low tissue-nonspecific alkaline phosphatase activity and associated with a range of signs and symptoms, including bone mineralization defects, respiratory problems, seizures, premature tooth loss, and fractures. Data from...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097329/ https://www.ncbi.nlm.nih.gov/pubmed/30115096 http://dx.doi.org/10.1186/s13023-018-0869-4 |