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Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease

BACKGROUND: There is accumulating evidence that synaptic loss precedes neuronal loss and correlates best with impaired memory formation in Alzheimer’s disease (AD). Cerebrospinal fluid (CSF) synaptosomal-associated protein 25 (SNAP-25) is a newly discovered marker indicating synaptic damage. We here...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Therriault, Joseph, Kang, Min Su, Ng, Kok Pin, Pascoal, Tharick A., Rosa-Neto, Pedro, Gauthier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097333/
https://www.ncbi.nlm.nih.gov/pubmed/30115118
http://dx.doi.org/10.1186/s13195-018-0407-6