Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a disease characterized by a progressive degeneration of motor neurons leading to paralysis. Our previous MRI diffusion tensor imaging studies detected early white matter changes in the spinal cords of mice carrying the G93A-SOD1 mutation. Here, we...

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Detalles Bibliográficos
Autores principales: Gatto, Rodolfo G., Amin, Manish Y., Deyoung, Daniel, Hey, Matthew, Mareci, Thomas H., Magin, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097419/
https://www.ncbi.nlm.nih.gov/pubmed/30128146
http://dx.doi.org/10.1186/s40035-018-0122-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097419/
https://www.ncbi.nlm.nih.gov/pubmed/30128146
http://dx.doi.org/10.1186/s40035-018-0122-z

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