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Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity
About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)–mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we explore telomere clustering and telomeric HR induced...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097467/ https://www.ncbi.nlm.nih.gov/pubmed/30118998 http://dx.doi.org/10.1016/j.neo.2018.07.004 |