Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)–mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we explore telomere clustering and telomeric HR induced...

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Detalles Bibliográficos
Autores principales: Liu, Haiying, Xie, Yujie, Zhang, Zepeng, Mao, Pingsu, Liu, Jingfan, Ma, Wenbin, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097467/
https://www.ncbi.nlm.nih.gov/pubmed/30118998
http://dx.doi.org/10.1016/j.neo.2018.07.004

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