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A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis

It has been reported that overactivation of fibroblast growth factor receptor 1 (FGFR1) is an important characteristic found in most non-small cell lung cancer (NSCLC) samples. Here, we identified a FGFR1 inhibitory peptide R1-P2 and investigated its effects on the lung cancer cells growth and angio...

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Detalles Bibliográficos
Autores principales: Tan, Qiaoyan, Wang, Zuqiang, Wang, Quan, Wang, Yuanqiang, Huang, Zhifeng, Su, Nan, Jin, Min, Kuang, Liang, Qi, Huabing, Ni, Zhenhong, Li, Can, Zhu, Ying, Jiang, Wanling, Chen, Hangang, Deng, Chuxia, Du, Xiaolan, Xie, Yangli, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097486/
https://www.ncbi.nlm.nih.gov/pubmed/30123084
http://dx.doi.org/10.7150/ijbs.24739