An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys

During terminal erythropoiesis, the splicing machinery in differentiating erythroblasts executes a robust intron retention (IR) program that impacts expression of hundreds of genes. We studied IR mechanisms in the SF3B1 splicing factor gene, which expresses ∼50% of its transcripts in late erythrobla...

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Detalles Bibliográficos
Autores principales: Parra, Marilyn, Booth, Ben W., Weiszmann, Richard, Yee, Brian, Yeo, Gene W., Brown, James B., Celniker, Susan E., Conboy, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097662/
https://www.ncbi.nlm.nih.gov/pubmed/29959282
http://dx.doi.org/10.1261/rna.066951.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097662/
https://www.ncbi.nlm.nih.gov/pubmed/29959282
http://dx.doi.org/10.1261/rna.066951.118

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