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Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition
Naturally-occurring chalcones and synthetic chalcone analogues have been demonstrated to have many biological effects, including anti-inflammatory, anti-malarial, anti-fungal, and anti-oxidant/anti-cancerous activities. Compared to other chalcones, trans-chalcone exhibits superior inhibitory activit...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097677/ https://www.ncbi.nlm.nih.gov/pubmed/30118500 http://dx.doi.org/10.1371/journal.pone.0202263 |