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TLR4-mediated activation of the ERK pathway following UVA irradiation contributes to increased cytokine and MMP expression in senescent human dermal fibroblasts

Exposure to ultraviolet (UV) radiation is a major contributing factor to premature aging (photoaging) and skin cancer. In vitro models of cellular senescence have proven to be very useful for the study of slow and progressive accumulation of damage resulting in the growth arrest of aging skin cells....

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Detalles Bibliográficos
Autores principales: Seo, Seong-Wook, Park, Seul-Ki, Oh, Soo-Jin, Shin, Ok Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097681/
https://www.ncbi.nlm.nih.gov/pubmed/30118525
http://dx.doi.org/10.1371/journal.pone.0202323