(Pro)Renin receptor mediates obesity-induced antinatriuresis and elevated blood pressure via upregulation of the renal epithelial sodium channel

Recent studies have demonstrated that the renal (pro)renin receptor (PRR) regulates expression of the alpha subunit of the epithelial sodium channel (α-ENaC). In this study we hypothesized that the renal PRR mediates high fat diet (HFD)-induced sodium retention and elevated systolic blood pressure (...

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Detalles Bibliográficos
Autores principales: Quadri, Syed S., Culver, Silas, Ramkumar, Nrupama, Kohan, Donald E., Siragy, Helmy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097690/
https://www.ncbi.nlm.nih.gov/pubmed/30118514
http://dx.doi.org/10.1371/journal.pone.0202419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097690/
https://www.ncbi.nlm.nih.gov/pubmed/30118514
http://dx.doi.org/10.1371/journal.pone.0202419

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