A novel recombinant human plasminogen activator: Efficient expression and hereditary stability in transgenic goats and in vitro thrombolytic bioactivity in the milk of transgenic goats

BACKGROUND: Thromboses is a rapidly growing medical problem worldwide. Low-cost, high-scale production of thrombotic drugs is needed to meet the demand. The production of biomolecules in transgenic animals might help address this issue. To our knowledge, the expression of recombinant human plasminog...

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Detalles Bibliográficos
Autores principales: He, Zhengyi, Lu, Rui, Zhang, Ting, Jiang, Lei, Zhou, Minya, Wu, Daijin, Cheng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097695/
https://www.ncbi.nlm.nih.gov/pubmed/30118482
http://dx.doi.org/10.1371/journal.pone.0201788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097695/
https://www.ncbi.nlm.nih.gov/pubmed/30118482
http://dx.doi.org/10.1371/journal.pone.0201788

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