Cargando…
Network-level allosteric effects are elucidated by detailing how ligand-binding events modulate utilization of catalytic potentials
Allosteric regulation has traditionally been described by mathematically-complex allosteric rate laws in the form of ratios of polynomials derived from the application of simplifying kinetic assumptions. Alternatively, an approach that explicitly describes all known ligand-binding events requires no...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097697/ https://www.ncbi.nlm.nih.gov/pubmed/30086174 http://dx.doi.org/10.1371/journal.pcbi.1006356 |