Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

Some secreted proteins that assemble into large complexes, such as extracellular matrices or hormones and enzymes in storage granules, must be kept at subaggregation concentrations during intracellular trafficking. We show surfeit locus protein 4 (Surf4) is the cargo receptor that establishes differ...

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Detalles Bibliográficos
Autores principales: Yin, Ying, Garcia, Mekka R., Novak, Alexander J., Saunders, Allison M., Ank, Raira S., Nam, Anna S., Fisher, Larry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097701/
https://www.ncbi.nlm.nih.gov/pubmed/30086131
http://dx.doi.org/10.1371/journal.pbio.2005140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097701/
https://www.ncbi.nlm.nih.gov/pubmed/30086131
http://dx.doi.org/10.1371/journal.pbio.2005140

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