α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

The antiepileptic drug ethosuximide has recently been shown to be neuroprotective in various Caenorhabditis elegans and rodent neurodegeneration models. It is therefore a promising repurposing candidate for the treatment of multiple neurodegenerative diseases. However, high concentrations of the dru...

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Detalles Bibliográficos
Autores principales: Wong, Shi Quan, Pontifex, Matthew G., Phelan, Marie M., Pidathala, Chandra, Kraemer, Brian C., Barclay, Jeff W., Berry, Neil G., O'Neill, Paul M., Burgoyne, Robert D., Morgan, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097874/
https://www.ncbi.nlm.nih.gov/pubmed/29940336
http://dx.doi.org/10.1016/j.nbd.2018.06.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097874/
https://www.ncbi.nlm.nih.gov/pubmed/29940336
http://dx.doi.org/10.1016/j.nbd.2018.06.013

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