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Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors
Betulin derivatives have been proven effective in vitro against Leishmania donovani amastigotes, which cause visceral leishmaniasis. Identifying the molecular targets and molecular mechanisms underlying their action is a currently an unmet challenge. In the present study, we tackle this problem usin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097978/ https://www.ncbi.nlm.nih.gov/pubmed/30120601 http://dx.doi.org/10.1186/s13321-018-0291-x |