Membrane-Modulating Drugs can Affect the Size of Amyloid-β(25–35) Aggregates in Anionic Membranes

The formation of amyloid-β plaques is one of the hallmarks of Alzheimer’s disease. The presence of an amphiphatic cell membrane can accelerate the formation of amyloid-β aggregates, making it a potential druggable target to delay the progression of Alzheimer’s disease. We have prepared unsaturated a...

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Detalles Bibliográficos
Autores principales: Khondker, Adree, Alsop, Richard J., Himbert, Sebastian, Tang, Jennifer, Shi, An-Chang, Hitchcock, Adam P., Rheinstädter, Maikel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098001/
https://www.ncbi.nlm.nih.gov/pubmed/30120270
http://dx.doi.org/10.1038/s41598-018-30431-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098001/
https://www.ncbi.nlm.nih.gov/pubmed/30120270
http://dx.doi.org/10.1038/s41598-018-30431-8

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