Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules

Tubulin polyglutamylation is a predominant axonemal post-translational modification. However, if and how axoneme polyglutamylation is essential for primary cilia and contribute to ciliopathies are unknown. Here, we report that Joubert syndrome protein ARL13B controls axoneme polyglutamylation, which...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Kai, Ma, Xiaoyu, Xu, Tao, Li, Yan, Hodge, Allen, Zhang, Qing, Torline, Julia, Huang, Yan, Zhao, Jian, Ling, Kun, Hu, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098020/
https://www.ncbi.nlm.nih.gov/pubmed/30120249
http://dx.doi.org/10.1038/s41467-018-05867-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098020/
https://www.ncbi.nlm.nih.gov/pubmed/30120249
http://dx.doi.org/10.1038/s41467-018-05867-1

Ejemplares similares