An intrinsic tumour eviction mechanism in Drosophila mediated by steroid hormone signalling

Polycomb group proteins are epigenetic regulators maintaining transcriptional memory during cellular proliferation. In Drosophila larvae, malfunction of Polyhomeotic (Ph), a member of the PRC1 silencing complex, results in neoplastic growth. Here, we report an intrinsic tumour suppression mechanism...

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Detalles Bibliográficos
Autores principales: Jiang, Yanrui, Seimiya, Makiko, Schlumpf, Tommy Beat, Paro, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098038/
https://www.ncbi.nlm.nih.gov/pubmed/30120247
http://dx.doi.org/10.1038/s41467-018-05794-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098038/
https://www.ncbi.nlm.nih.gov/pubmed/30120247
http://dx.doi.org/10.1038/s41467-018-05794-1

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