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AIEC infection triggers modification of gut microbiota composition in genetically predisposed mice, contributing to intestinal inflammation

A high prevalence of adherent-invasive E. coli (AIEC) in the intestinal mucosa of Crohn’s disease patients has been shown. AIEC colonize the intestine and induce inflammation in genetically predisposed mouse models including CEABAC10 transgenic (Tg) mice expressing human CEACAM6-receptor for AIEC an...

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Detalles Bibliográficos
Autores principales: Bretin, Alexis, Lucas, Cécily, Larabi, Anaïs, Dalmasso, Guillaume, Billard, Elisabeth, Barnich, Nicolas, Bonnet, Richard, Nguyen, Hang Thi Thu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098085/
https://www.ncbi.nlm.nih.gov/pubmed/30120269
http://dx.doi.org/10.1038/s41598-018-30055-y