UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy

Clearance of damaged mitochondria through mitophagy is critical for maintaining mitochondrial fidelity and the prevention of neurodegeneration. Here, we report on the UBX domain-containing, p97/VCP cofactor UBXD1/UBXN6/UBXDC2 and its role in mitophagy. Recognizing depolarized mitochondria via its C-...

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Detalles Bibliográficos
Autores principales: Bento, Ana C., Bippes, Claudia C., Kohler, Corina, Hemion, Charles, Frank, Stephan, Neutzner, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098094/
https://www.ncbi.nlm.nih.gov/pubmed/30120381
http://dx.doi.org/10.1038/s41598-018-30963-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098094/
https://www.ncbi.nlm.nih.gov/pubmed/30120381
http://dx.doi.org/10.1038/s41598-018-30963-z

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