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Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes
Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated (p-value < 5 × 10(−8)) with diabetic albuminuria, in Fi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098108/ https://www.ncbi.nlm.nih.gov/pubmed/30120300 http://dx.doi.org/10.1038/s41598-018-29211-1 |