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Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes

Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated (p-value < 5 × 10(−8)) with diabetic albuminuria, in Fi...

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Detalles Bibliográficos
Autores principales: Sandholm, Niina, Haukka, Jani K, Toppila, Iiro, Valo, Erkka, Harjutsalo, Valma, Forsblom, Carol, Groop, Per-Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098108/
https://www.ncbi.nlm.nih.gov/pubmed/30120300
http://dx.doi.org/10.1038/s41598-018-29211-1

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