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Multiple domains of bacterial and human Lon proteases define substrate selectivity

The Lon protease selectively degrades abnormal proteins or certain normal proteins in response to environmental and cellular conditions in many prokaryotic and eukaryotic organisms. However, the mechanism(s) behind the substrate selection of normal proteins remains largely unknown. In this study, we...

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Detalles Bibliográficos
Autores principales: He, Lihong, Luo, Dongyang, Yang, Fan, Li, Chunhao, Zhang, Xuegong, Deng, Haiteng, Zhang, Jing-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098112/
https://www.ncbi.nlm.nih.gov/pubmed/30120231
http://dx.doi.org/10.1038/s41426-018-0148-4