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Linear mapping approximation of gene regulatory networks with stochastic dynamics
The presence of protein–DNA binding reactions often leads to analytically intractable models of stochastic gene expression. Here we present the linear-mapping approximation that maps systems with protein–promoter interactions onto approximately equivalent systems with no binding reactions. This is a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098115/ https://www.ncbi.nlm.nih.gov/pubmed/30120244 http://dx.doi.org/10.1038/s41467-018-05822-0 |